Short Term Stability Testing of Efavirenz-Loaded Solid Lipid Nanoparticle (SLN) and Nanostructured Lipid Carrier (NLC) Dispersions

Solid Lipid Nanoparticles (SLN) and Nanostructured Lipid Carriers (NLC): Occlusive Effect and Penetration Enhancement Ability

Objective: This work compares the occlusive effect and the penetration enhancement ability of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), through in vitro skin. Methods: SLN and NLC were prepared by high shear homogenization and characterized by size, polydispersity index, zeta potential, morphology and physical stability. Occlusive effect was assessed by an in vitr...

Moisturizing effects of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) using deionized and magnetized water by in vivo and in vitro methods

Objective(s): The present study aimed to determine and compare moisturizing and occlusion effects of different solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) using magnetized water and deionized water.Materials and Methods: SLN formulations were prepared using various lipids, including Tripalmitin, Compritol®, Pr...

Formulation and Characterization of [6]-gingerol Loaded Nanostructured Lipid Carrier (nlc)

Nanostructured lipid carrier (NLC) is the blend of solid lipid, liquid lipid and suitable surfactant for the purpose of encapsulated poorly water soluble drugs. [6]-gingerol is the main bioactive compound in Zingiber officinale, widely known as ginger in Malaysia. Zingiber officinale extract has been discovered to have anti-oxidant, anti-inflammatory, and anti-microbial effects to human body. T...

Itraconazol-Loaded Nanostructured Lipid Carriers (NLC) for Pulmonary Application

Rosuvastatin Loaded Nanostructured Lipid Carrier: For Enhancement of Oral Bioavailability

Rosuvastatin is a lipid lowering agent, which has low solubility and low bioavailability of 20% with oral administration. Therefore the present study was undertaken to improve solubility and bioavailability of Rosuvastatin by formulating it into Nano structured lipid carriers (NLCs) by using stearic acid and Compritol ATO 888 as solid-lipid, Oleic acid as liquid-lipid and Poloxamer 188 as a sur...